The higher the hemoglobin A1c, the higher your risk of having complications related to diabetes. Overall, the mean age was 57 years, 55% were women, and 24% were black. The HRs were adjusted for age, sex, race, field center, total and HDL cholesterol, BMI, waist-to-hip ratio, hypertension, family history of diabetes, education level, alcohol use, physical activity, smoking status, hemoglobin, MCV, fibrinogen, and leukocyte count. This article describes why A1c is used in the first place, as well as factors that can lead to misleadingly high or low … See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details. Compared with persons with HbA1c in the normal range, we found that low HbA1c values (<5.0%) were associated with an increased risk of all-cause mortality and death from various causes, including cancer. 2. GP said if I kept up, I'd probably come off the Metformin. Introduction. A bit looser goal (such as less than 8 percent) may be fine for those with advanced diabetes complications, other chronic illnesses, or shorter life expectancies. An A1c less than 7% means your a in a healthy range. Introduction. An A1c of 4.4 is Normal. Extremely low hemoglobin A1c (HbA1c) results below reference range are rare, and the causes and clinical implications associated with low HbA1c results are not well understood among clinical laboratorians. Once your A1c is 9% and higher, immediate action should be taken to get your sugars down because you are in a dangerous zone. We excluded participants who self-identified as other than white or black race (n = 48) or who were missing data on HbA1c or other covariates of interest (n = 970), leaving a final sample size of 13,288 participants in this analysis. Medications can do a lot to reduce blood sugar but lifestyle changes remain a centerpiece of treatment. A1C test results are reported as a percentage. Once you enter your A1c result, the analyzer will determine if your result is low, optimal, or high and what that might mean. To ensure that your blood sugar level is not brought too low, measure your level every single day for at least for the first two weeks. A number of studies have demonstrated that HbA1c values, even below the diagnostic threshold of 6.5%, are associated with clinical outcomes including cardiovascular events (3–5), kidney disease (6), and total mortality (3,7–9). is the guarantor of this work and, as such, had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. When is someone’s A1C “too low”? ; The blood test for HbA1c level is routinely performed in people with type 1 and type 2 diabetes mellitus. This work was supported by NIH/NIDDK grant R21-DK-080294. However, people may experience temporary pain or … If too much medication is forcing you below 6.0, you’re staring at a yellow light. Of the total 13,288 participants included in this study, 1,113 (8.4%) participants died of cancer, 1,085 (8.2%) died of cardiovascular disease, 235 (1.8%) died of respiratory system disease, 82 (0.6%) died of digestive system or liver disease, and 61 (0.5%) died of genitourinary system or kidney disease. The American Diabetes Association (ADA) recommends that many adults with diabetes strive to keep A1C less than 7percent, but the goal can differ from person to person. The American Diabetes Association (ADA) recommends that many adults with diabetes strive to keep A1C less than 7 percent, but the goal can differ from person to person. Certain limitations should be considered in interpreting the results of this study. For someone who doesn't have … Two models were used: model 1 was adjusted for age, sex, and race/field center, and model 2 was adjusted for the variables in model 1 plus total and HDL cholesterol, BMI, waist-to-hip ratio, hypertension, family history of diabetes, education level, alcohol use, physical activity, smoking status, hemoglobin, MCV, fibrinogen, and leukocyte count. and decreased my prescription. Diagnosis and classification of diabetes mellitus, Glycated hemoglobin, diabetes, and cardiovascular risk in nondiabetic adults, Markers of dysglycaemia and risk of coronary heart disease in people without diabetes: Reykjavik prospective study and systematic review, Association of hemoglobin A1c with cardiovascular disease and mortality in adults: the European prospective investigation into cancer in Norfolk, Glycated hemoglobin and the risk of kidney disease and retinopathy in adults with and without diabetes, A New Zealand linkage study examining the associations between A1C concentration and mortality, HbA1c measured in stored erythrocytes and mortality rate among middle-aged and older women, Survival as a function of HbA(1c) in people with type 2 diabetes: a retrospective cohort study, Low hemoglobin A1c and risk of all-cause mortality among US adults without diabetes, Low glycated hemoglobin and liver disease in the U.S. population, The Atherosclerosis Risk in Communities (ARIC) Study: design and objectives. Visit 2 (1990–1992) was attended by 14,348 participants and is the baseline for the present analysis. But he said 6.1 was too low. Ideally it should not be greater than 1/3 of the overall average blood sugar. This will quickly lower your blood sugar level. This hypothesis is consistent with the negative confounding observed in our study; once traditional risk factors for death were added to our models, the association of low HbA1c with all-cause mortality and cause-specific mortality became stronger. Is the current definition for diabetes relevant to mortality risk from all causes and cardiovascular and noncardiovascular diseases? Diabetes can increase your risk of: Whereas high HbA1c values are almost entirely determined by circulating glucose levels (27), it is probable that nonglycemic factors such as red-cell turnover may be of disproportionate importance in the low range of HbA1c. The first study visit occurred between 1987 and 1989 with three follow-up visits that occurred approximately every 3 years (13,14). Many Doctors complain that by today’s 20 years old definition of A1C 6.5% until reached already too many damages occur. In non-Ds (non-Diabetics), the glycated haemoglobin level, or HbA1c level, ranges from 3.5% to 5.5% - so at 4.0%, you’re test is near the low end - of NORMAL. Baseline characteristics of the study population by HbA1c category at baseline (ARIC visit 2). Lifestyle changes with A1c of 10.4. This question is for testing whether or not you are a human visitor and to prevent automated spam submissions. , too is 4 % to 5.9 % but it doesn ’ t replace blood... 29 ( a1c too low ) ( 28 ) important tool for managing diabetes but! You below 6.0, you ’ re staring at a yellow light the case here lost over 30.! 11 ( StataCorp, College Station, TX ) HbA1c may also increase mortality increased mortality was also reported J-shaped... 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